Core Facilities

MMRI has 31,000 square feet of space including laboratories, offices, library, conference rooms, common areas, and kitchen. We are conveniently located in the heart of Silicon Valley, a few minutes from Stanford University, the NASA space research center, and numerous biotechnology companies. The Institute occupies a modern facility capable of supporting our efforts in molecular biology, immunology, cell biology, synthetic organic chemistry and is supported by a complete analytical chemistry laboratory.

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Cellular and Molecular Biology

The Cellular and Molecular Biology Laboratory at MMRI provides outstanding technical and scientific support for scientists within the Institute as well as our collaborators. Capabilities include:

In vitro

  • Tissue culture
  • Cell biology
  • Molecular biology

Assay Technology

  • Bioluminescence
  • FACS

Radioisotopic assay technologies



  • Immunohistochemistry
  • Fluorescent microscopy and image capture

Selected Equipment

  • Fluorescent microscope (inverted)
  • RT PCR
  • 96-well UV-Vis and fluorescence/ luminescence spectrophometers
  • Cell culture rooms equipped with biosafety cabinets
  • Electrophoresis
  • Packard Topcount NXT (microplate liquid scintillation and luminescence)
  • Beckman LS 6500 liquid scintillation counter
  • LKB Wallac 1274 RiaGamma automatic gamma counter
  • Centrifuges (ultra, low speed, and bench top)
  • Fume hoods
  • Phosphorimager
  • Cryostats and microtomes
  • Perkin Elmer Piezorray high precision and high density microarraying system
  • Lyophilizer

Medicinal Chemistry

The Medicinal Chemistry Laboratory at MMRI is a modern facility with state-of- the-art equipment for small to medium scale synthesis, purification, and identification. Capabilities include:

Small to medium scale synthesis

Identification by MS and HPLC

Separation and purification by preparative HPLC


Selected Equipment

  • Fume hoods
  • Rotovaps
  • Extensive collection of specialized chemistry glassware
  • Vacuum pumps and circulating water vacuum aspirators
  • Gas chromatographs (FID and TCD)
  • Agilent 1100 LC-MSD (Electrospray and APCI)
  • Preparative and analytical HPLCs with UV-vis diode array detection
  • Teledyne CombiFlash automated synthesis systems

Analytical Chemistry

The Analytical Chemistry Laboratory at MMRI provides outstanding analytical support for internal research and in support of external collaborations. Capabilities include:

Mass Spectrometry

  • Molecular mass characterization
  • Quantitation of molecules in complex mixtures, formulations and biological matrices
  • Custom Analysis


  • Methods development
  • HPLC purity analysis
  • Quantitation of compounds in solution
  • Purification of compounds by preparative HPLC

Selected Equipment

  • Gas Chromatographs (FID and TCD)
  • Agilent 1100 LC-MSD (Electrospray and APCI)
  • Preparative and analytical HPLCs with UV-vis diode array detection
  • API 5000 LC/MS/MS

Licenses and Accreditations

  • DEA Licenses
  • Environmental Protection Agency Licenses
  • Environmental Health and Safety
  • Hazardous Material Licenses
  • Irradiation License
  • Radioactive Materials License

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